Which symptom could be a sign of excessive absorption of a topical corticosteroid?

Increased skin thickness is a symptom that can indicate excessive absorption of a topical corticosteroid. This phenomenon is often referred to as skin atrophy, where prolonged use or overuse of corticosteroids can lead to thinning of the skin and other structural changes. When topically applied corticosteroids are absorbed into the deeper layers of the skin, they can disrupt the normal regenerative processes of skin cells, potentially causing changes in skin texture and thickness.

In contrast, local rash can occur from irritation or allergic reactions to the topical product itself rather than from absorption issues. Systemic hypertension and facial flushing are more commonly associated with systemic effects of corticosteroids, which typically arise from oral or parenteral administration rather than topical use. Therefore, the correct response pointing to increased skin thickness aligns with the potential consequences of excessive absorption of a topical corticosteroid.