Which medications are classified as H2-receptor antagonists? Select all that apply.

H2-receptor antagonists, also known as H2 blockers, are a class of medications that reduce stomach acid production by blocking histamine at the H2 receptors in the stomach lining. This class is primarily used to treat conditions such as gastroesophageal reflux disease (GERD), peptic ulcers, and conditions that cause excessive stomach acid production.

Nizatidine, Ranitidine, and Famotidine belong to this class. Nizatidine (Axid) is effective in decreasing gastric acid secretion, which is the primary mechanism for reducing symptoms associated with acid reflux and ulcers. Ranitidine (Zantac), while it has come under scrutiny and has faced recalls in recent years due to potential contamination issues, is also recognized as an H2-receptor antagonist that has been widely used in the past. Famotidine (Pepcid) is another strong example of an H2-receptor antagonist that provides effective relief for acid-related disorders and is still commonly prescribed.

Esomeprazole (Nexium), on the other hand, is a proton pump inhibitor (PPI) rather than an H2-receptor antagonist. PPIs work by a different mechanism to inhibit acid production in the stomach, making it distinct from the H2