Which laboratory value should a nurse monitor for a client receiving busulfan (Myleran)?

Monitoring uric acid levels is particularly important for a client receiving busulfan due to the potential for tumor lysis syndrome, which can occur when large numbers of cancer cells are destroyed quickly. This destruction can release purines into the bloodstream, leading to increased production of uric acid as the body metabolizes these substances. High uric acid levels can result in hyperuricemia, which can cause complications such as gout or renal impairment if not monitored and managed properly.

In the context of busulfan therapy, the focus on uric acid is crucial, as the drug is often effective in treating certain malignancies but may also induce rapid cell turnover. Therefore, maintaining awareness of uric acid levels allows for timely interventions to prevent serious outcomes associated with elevated levels.

Other laboratory values, while important in general patient care, do not have the same direct association with busulfan therapy and its metabolic effects.