Which laboratory result indicates an adverse effect in a client taking tacrolimus (Prograf)?

Taking tacrolimus, an immunosuppressant used to prevent organ transplant rejection, can lead to several potential side effects, including impacts on blood glucose levels. A blood glucose level of 200 mg/dL is considered elevated and indicates the possibility of hyperglycemia, which is a common adverse effect associated with the use of tacrolimus. Elevated blood sugar levels can indicate the development of diabetes or worsen existing diabetes, thus making this laboratory result particularly significant in monitoring a patient’s response to tacrolimus therapy.

The other laboratory results mentioned do not typically suggest adverse effects related to tacrolimus. For instance, a potassium level of 3.8 mEq/L falls within the normal range and does not indicate a toxicity or an adverse effect. Similarly, a platelet count of 300,000 cells/mm³ is also within the normal range for adults, indicating adequate platelet production and function, which is important in patients receiving immunosuppressive therapy. Lastly, a white blood cell count of 6000 cells/mm³ is also considered normal and suggests no current issues with immune function or bone marrow suppression, both of which could be concerns when managing patients on tacrolimus.