When applying a topical corticosteroid for eczema, where should the nurse monitor for increased systemic absorption?

The axilla, or armpit area, is particularly significant when considering systemic absorption of topical corticosteroids. This is due to the thin skin in this region, which can allow for enhanced penetration of medications into the systemic circulation. Additionally, the axillary area is prone to occlusion, as it may often be covered by clothing or the arms themselves, which can further increase absorption.

In contrast, other areas like the back, soles of the feet, and palms of the hands have thicker skin and less likelihood of systemic absorption. While the back may facilitate moderate absorption, it does not compare to the higher absorption potential seen in the axillary region. The soles of the feet and palms of the hands are the thickest areas of skin on the body, designed to protect underlying tissues and usually limit the systemic absorption of topical treatments. Thus, when using corticosteroids for treating eczema, careful monitoring in the axiliary area is warranted to prevent potential systemic effects.