What adverse effect should the nurse monitor for in a client taking nevirapine (Viramune)?

Nevirapine (Viramune) is a non-nucleoside reverse transcriptase inhibitor (NNRTI) used in the treatment of HIV. One of the most common and significant adverse effects associated with nevirapine therapy is the development of a rash. This rash can vary from mild to severe, and in some cases, it may progress to more serious conditions such as Stevens-Johnson syndrome or toxic epidermal necrolysis.

Monitoring for rash is crucial, especially during the first few weeks of therapy, as it can indicate an allergic reaction or hypersensitivity to the medication. Early identification and management of this side effect are important to prevent more severe reactions which could lead to complications.

In addition to monitoring the rash, healthcare providers also need to remain vigilant for other less common side effects, but the risk and impact of rash make it a primary concern when caring for patients on nevirapine.