Metoclopramide can be safely administered to a patient with which condition?

Metoclopramide is a medication primarily used to treat nausea and vomiting. It works by enhancing gut motility and accelerating gastric emptying while also acting on the brain's chemotrigger zone to reduce the sensation of nausea.

In the context of cancer chemotherapy, patients often experience severe nausea and vomiting as side effects of their treatment. Metoclopramide can be safely administered to these patients to help alleviate these symptoms, making it an appropriate choice for managing chemotherapy-induced nausea and vomiting.

The other conditions listed involve scenarios where the use of metoclopramide is contraindicated due to the risk of increasing gastrointestinal motility in potentially harmful situations. For example, in cases of intestinal obstruction or diverticulitis with perforation, enhanced motility could worsen the patient's condition or lead to serious complications. Additionally, metoclopramide is not ideal in managing a peptic ulcer with melena, as it could mask symptoms and complicate the diagnosis and treatment.

Thus, the correct choice reflects the specific context where metoclopramide's action is beneficial and safe, demonstrating its effectiveness in managing nausea and vomiting associated with cancer chemotherapy.