If a nurse is applying a topical glucocorticoid to a client with eczema, where should they monitor for systemic absorption?

Monitoring for systemic absorption of a topical glucocorticoid is particularly important in areas of the body where the skin is more permeable and where absorption rates can be higher. The axilla is an area with thin skin and high vascularity, which can facilitate greater absorption of topical medications. Due to the increased skin permeability in the axillary region, there is a higher risk for systemic effects when glucocorticoids are applied there.

In contrast, areas like the back, soles of the feet, and palms of the hands have more thick and keratinized skin, which generally decreases the absorption rate of topical medications. Thus, systemic absorption is less likely to occur in these regions. Therefore, monitoring in areas with thinner skin, such as the axilla, is essential to ensure that the client does not experience unwanted systemic effects from the topical glucocorticoid.