How should the client take ibuprofen (Advil) as advised by the nurse?

The recommendation to take ibuprofen with 8 oz of milk is based on the fact that ibuprofen can irritate the stomach lining. Consuming it with milk or food can help mitigate this potential gastrointestinal irritation, making it easier on the stomach and reducing the risk of side effects such as nausea or ulcers. Milk provides a coating effect and buffers the acidity, thus enhancing tolerance and safety when taking this medication.

Taking ibuprofen in the morning after arising, 60 minutes before breakfast, or at bedtime on an empty stomach does not provide the same protective effects against gastric irritation. Therefore, the safest and most effective method for taking ibuprofen is with milk, which supports the body's digestive processes and minimizes discomfort.