Before administering disulfiram (Antabuse), which information is most important for the nurse to gather?

Gathering the information regarding when the last alcoholic drink was consumed is crucial before administering disulfiram (Antabuse). Disulfiram is a medication used in the treatment of alcohol dependence; it works by blocking the metabolism of alcohol, resulting in unpleasant reactions if alcohol is consumed. These reactions can include flushing, nausea, vomiting, and even more severe symptoms, which can pose significant health risks.

To prevent these adverse effects, it is essential for the nurse to confirm that the patient has abstained from alcohol for a suitable period, typically at least 12 hours before starting disulfiram. Understanding the timing of the last alcoholic drink helps ensure the patient's safety and enhances the effectiveness of the treatment plan for alcohol dependence. This information guides the nurse in their assessment and decision-making process regarding the administration of the medication.

The other options, while they could be relevant in different contexts, do not hold the same level of immediate importance concerning the administration of disulfiram. Information related to hyperthyroidism, the timing of meals, and diabetes insipidus may be significant considerations in other patient assessments, but they do not directly impact the acute management related to disulfiram and its interactions with alcohol consumption.