An acetazolamide dose is prescribed based on BSA of 0.7 m2. If the total daily dose is 600 mg/m2, what is the mg per dose?

To determine the correct dosage per dose of acetazolamide, first calculate the total daily dose based on the body surface area (BSA). The prescribed total daily dose is 600 mg/m², and the patient's BSA is 0.7 m².

To find the total daily dose, you multiply the total daily dose per square meter by the patient's BSA:

600 mg/m² × 0.7 m² = 420 mg per day.

Next, the typical practice for dosing involves dividing the total daily dose into multiple doses. In scenarios where a common dosing schedule is used, such as two or three doses per day, the total daily amount can be divided by the number of doses taken throughout the day. With a division yielding a feasible per dose amount, it is necessary to identify a standard regimen.

If we assume a standard twice-daily dosing schedule, you would divide the total daily dose by 2:

420 mg per day ÷ 2 doses per day = 210 mg per dose.

However, looking at the choices provided, it's more unusual to see 210 mg per dose, leading to a review of dividing by a different number of doses, like three. If we consider three doses in a day: