A client taking ticlopidine hydrochloride (Ticlid) should avoid which of the following medications?

Ticlopidine hydrochloride (Ticlid) is an antiplatelet medication that works by inhibiting platelet aggregation, which helps to prevent blood clots. When considering potential interactions with other medications, it is essential to recognize that the combination of ticlopidine with acetylsalicylic acid (aspirin) can significantly increase the risk of bleeding. Both drugs have an antiplatelet effect, and when taken together, they can lead to a heightened risk of gastrointestinal bleeding and other bleeding complications.

Due to the shared mechanism of action of ticlopidine and aspirin, healthcare providers generally recommend avoiding concurrent use unless the benefits clearly outweigh the risks and it is closely monitored by a healthcare professional. Therefore, it is vital for a client taking ticlopidine to steer clear of aspirin unless directed otherwise by their physician, making it the correct choice for this question.

The other medications listed, such as Vitamin C, acetaminophen, and Vitamin D, do not carry the same risks of increasing bleeding when taken with ticlopidine, making them safer alternatives in the context of managing a patient on this antiplatelet therapy.