A client taking phenelzine sulfate (Nardil) is advised to avoid which of the following foods?

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Phenelzine sulfate (Nardil) is a monoamine oxidase inhibitor (MAOI) used to treat depression, and it is crucial for patients on MAOIs to avoid certain foods that can interact with the medication. Specifically, aged cheeses are known to contain high levels of tyramine, which can lead to severe hypertensive crises when consumed by individuals taking MAOIs like phenelzine.

Tyramine is an amino acid that can cause blood pressure to rise significantly when it interacts with the inhibited monoamine oxidase enzyme. Aged cheeses are particularly high in tyramine due to the fermentation process they undergo. Therefore, it is critical that patients on phenelzine avoid aged cheese to prevent adverse reactions.

While figs, yogurt, and crackers may have less concern regarding tyramine content, aged cheese is a well-documented food to avoid for those on MAOIs due to the risk of potentially dangerous interactions. Understanding the specificity of food interactions when taking an MAOI is essential for maintaining patient safety and effective treatment outcomes.

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