A client receiving nitrofurantoin (Macrodantin) reports side effects. Which side effect indicates the treatment should be stopped?

Cough and chest pain are significant side effects that warrant immediate cessation of nitrofurantoin treatment. Nitrofurantoin is known to potentially cause pulmonary reactions, which can manifest as cough, chest pain, or difficulty breathing. These symptoms may indicate a serious adverse reaction, such as acute pulmonary toxicity or hypersensitivity reactions, which could lead to more severe complications if not addressed promptly.

The presence of these symptoms suggests that the patient could be experiencing a severe lung reaction, which necessitates stopping the medication and assessing the patient further. While nausea, diarrhea, and anorexia are side effects that can occur with nitrofurantoin, they are generally less severe and can often be managed without discontinuing the medication. Recognizing and responding to more critical side effects like cough and chest pain is essential for patient safety.